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Human Peripheral Blood Neutrophil Isolation for Interrogating the Parkinson's Associated LRRK2 Kinase Pathway by Assessing Rab10 Phosphorylation
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Analysis of exon dosage using MLPA in South African Parkinson's disease patients
Rowena J Keyser1, Debbie Lombard, Rene Veikondis
1Division of Molecular Biology and Human Genetics, Faculty of Health Sciences, University of Stellenbosch, Tygerberg, Cape Town, South Africa. rowenak@sun.ac.za
Neurogenetics
|December 17, 2009
Abstract:
Genomic rearrangements (exon dosage) are common mutations reported in Parkinson's disease (PD) patients. In the present study, we aimed to investigate the prevalence of genomic rearrangements in 88 South African patients with predominantly early-onset PD (age-at-onset
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