Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Disorders of the Skeletal Muscle

Disorders of the Skeletal Muscle

The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Beyond evidence supremacy: Reclaiming the Clinician's role through the integration of structural and existential approaches in daily practice.

Modern rheumatology·2026

Same author

Efficacy and Safety of Tofacitinib and Adalimumab in Rheumatoid Arthritis by Body Mass Index-Normalized Methotrexate Dose: A Post Hoc Analysis.

Rheumatology and therapy·2026

Same author

Factors associated with treatment discontinuation and age-stratified safety of abatacept in Japanese patients with rheumatoid arthritis: 5-year results of the ORIGAMI study.

Modern rheumatology·2025

Same author

Letter to the Editor Regarding "Evaluation of VTE, MACE, and Serious Infections Among Patients with RA Treated with Baricitinib Compared to TNFi: A Multi-Database Study of Patients in Routine Care Using Disease Registries and Claims Databases".

Rheumatology and therapy·2025

Same author

Response to the Letter to the Editor: "Rheumatoid arthritis and subsequent fracture risk".

Journal of bone and mineral metabolism·2025

Same author

Mortality and risk factors in Japanese patients with rheumatoid arthritis: a 14-year observation of the IORRA cohort.

Modern rheumatology·2025

Search research articles

Related Experiment Video

Updated: Jun 17, 2026

A Passive Ankle Dorsiflexion Testing System for an In Vivo Model of Overuse-induced Tendinopathy

A Passive Ankle Dorsiflexion Testing System for an In Vivo Model of Overuse-induced Tendinopathy

Published on: March 1, 2024

Multiple extensor tendon ruptures caused by tophaceous gout.

Takuji Iwamoto¹, Hiroe Toki, Katsunori Ikari

¹Institute of Rheumatology, Tokyo Women's Medical University, 10-22 Kawada, Shinjuku, Tokyo, 162-0054, Japan. iwatakuji@gmail.com

Modern Rheumatology

|December 17, 2009

Summary

Gouty tophi can cause painless hand masses and finger stiffness. This condition should be considered in the diagnosis of chronic extensor tenosynovitis.

More Related Videos

Biomechanical Testing of Murine Tendons

Biomechanical Testing of Murine Tendons

Published on: October 15, 2019

Related Experiment Videos

Last Updated: Jun 17, 2026

A Passive Ankle Dorsiflexion Testing System for an In Vivo Model of Overuse-induced Tendinopathy

A Passive Ankle Dorsiflexion Testing System for an In Vivo Model of Overuse-induced Tendinopathy

Published on: March 1, 2024

Biomechanical Testing of Murine Tendons

Biomechanical Testing of Murine Tendons

Published on: October 15, 2019

Area of Science:

Rheumatology
Orthopedic Surgery
Hand Surgery

Background:

Chronic extensor tenosynovitis of the hand can present with insidious onset of pain and functional loss.
Differential diagnosis often includes inflammatory arthritis, infections, and neoplastic processes.

Observation:

A 54-year-old woman developed painless subcutaneous masses on her right hand with spontaneous loss of ring finger extension.
Surgical wrist exploration revealed hypertrophic, white crystal deposits surrounding and invading extensor tendons.

Findings:

Histopathology confirmed the deposits as gouty tophi, indicative of chronic gouty arthritis.
The findings highlight intratendinous invasion by tophaceous deposits.

Implications:

Tophaceous gout should be considered in the differential diagnosis of chronic extensor tenosynovitis of the hand.
This case underscores the importance of considering metabolic conditions in hand pathology.
Early recognition can guide appropriate management and prevent further tendon damage.