A new anthraquinone derivative from the marine endophytic fungus Fusarium sp. (No. b77)
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Updated: Jun 17, 2026

Sexual Development and Ascospore Discharge in Fusarium graminearum
Published on: March 29, 2012
Changlun Shao1, Changyun Wang, Caijuan Zheng
1School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, P.R. China.
Abstract:
A new anthraquinone compound, 5-acetyl-2-methoxy-1,4,6-trihydroxy-anthraquinone (1), together with four known naphthoquinones (2-5), were isolated from the culture of the mangrove fungus (No. b77). All the isolated compounds (1-5) and the acetyl derivative (1a) were established by comprehensive analysis of the spectral data, especially 1D- and 2D-NMR (HMQC and HMBC) spectra. In the primary bioassays, compound 3 showed strong inhibitory effects on the growth of hepG2 and hep2 cells, with IC(50) values of 1.0 and 2.5 microg mL(-1), respectively.
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