LDH isoenzyme electrophoretic pattern differences between colloid and other adenocarcinomas of the colon

LDH isoenzyme electrophoretic patterns have been studied in 27 adenocarcinomas of the colon. The different content of M monomer in poorly differentiated tumors is statistically significant (P less than 0.001) when compared to well-differentiated tumors of the colon. Such a difference has not been found for two Broders groups of well-differentiated tumors. A commentary is made on the possibilities of histochemistry and cytochemistry providing better classification of these tumors.