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Protein incorporation in giant lipid vesicles under physiological conditions

Paige M Shaklee1, Stefan Semrau, Maurits Malkus

  • 1Physics of Life Processes, Leiden Institute of Physics, Leiden University, Niels Bohrweg 2, 2333 CA, Leiden, The Netherlands. p.shaklee@amolf.nl

Chembiochem : a European Journal of Chemical Biology
|December 17, 2009
PubMed
Abstract

No abstract available in PubMed .

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In the plasma membrane, the lipids forming the bilayer can also act as an anchor to tether proteins to the membrane. The three main types of lipid anchors found in eukaryotes are – prenyl groups, fatty acyl groups, and glycosylphosphatidylinositol or GPI groups. Prenyl and fatty acyl groups act as anchors on the cytosolic surface of the membrane, whereas GPI anchors proteins on the extracellular side.
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