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Updated: Jun 17, 2026

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
Published on: February 7, 2017
DBU catalysis of N,N'-carbonyldiimidazole-mediated amidations
Claude Larrivée-Aboussafy1, Brian P Jones, Kristin E Price
1Development Science and Technology, Pfizer Inc., Eastern Point Road, Groton, Connecticut 06340, USA.
Abstract:
1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) has been found to catalyze the amidation of acyl imidazoles. The rate acceleration is especially evident with traditionally unreactive, electron-deficient anilines. DBU is readily available and offers safety and cost advantages over more commonly employed catalysts such as 1-hydroxybenzotriazole.
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