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Efficient Derivation of Human Neuronal Progenitors and Neurons from Pluripotent Human Embryonic Stem Cells with Small Molecule Induction
Published on: October 28, 2011
Discovery of a new and efficient small molecule for neuronal differentiation from mesenchymal stem cell
Na Ri Kim1, Seung Kyu Kang, Hyun Hee Ahn
1Korea Research Institute of Chemical Technology, Daejeon, 305-600, Korea.
Journal of Medicinal Chemistry
|December 18, 2009
Abstract:
A new synthetic small molecule, compound 1, which induced a neuronal differentiation from mesenchymal stem cells (MSCs) with an excellent efficiency, was identified. Furthermore the differentiated cell by 1 showed the neural electrophysiological and cholinergic neuron properties.
