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Related Concept Videos

Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
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An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
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Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...

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Related Experiment Video

Updated: Jun 17, 2026

Assessment of Cardiac Function and Myocardial Morphology Using Small Animal Look-locker Inversion Recovery (SALLI) MRI in Rats
08:41

Assessment of Cardiac Function and Myocardial Morphology Using Small Animal Look-locker Inversion Recovery (SALLI) MRI in Rats

Published on: July 19, 2013

Cardiovascular MRI in small animals.

Marcus R Makowski1, Andrea J Wiethoff, Christian H P Jansen

  • 1Division of Imaging Sciences, King's College London, 4th Floor, Lambeth Wing, St Thomas' Hospital, London SE1 7EH, UK. marcus.makowski@kcl.ac.uk

Expert Review of Cardiovascular Therapy
|December 18, 2009
PubMed
Summary
This summary is machine-generated.

Magnetic resonance imaging (MRI) is crucial for preclinical cardiovascular research in rodent models. Advances in MRI hardware, sequences, and contrast agents enable detailed anatomical, functional, and molecular imaging of cardiovascular disease.

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Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for In Vivo Phenotyping and Drug Monitoring

Published on: June 23, 2015

Area of Science:

  • Cardiovascular Research
  • Medical Imaging
  • Preclinical Studies

Background:

  • Small rodent models are essential for preclinical cardiovascular research.
  • Genetically altered models help investigate gene influence on cardiovascular disease pathogenesis.
  • In vivo platforms are vital for testing new drugs and contrast agents.

Purpose of the Study:

  • To review recent advancements in MRI hardware, imaging sequences, and probe design for cardiovascular research.
  • To highlight the utility of MRI in assessing cardiovascular anatomy and function in preclinical models.
  • To discuss the application of targeted MRI contrast agents for molecular imaging of cardiovascular disease.

Main Methods:

  • Review of recent literature on MRI techniques in cardiovascular research.
  • Focus on hardware, imaging sequences, and contrast agent development.
  • Emphasis on applications in genetically altered rodent models.

Main Results:

  • MRI offers excellent soft tissue contrast, high spatial and temporal resolution, and tomographic capabilities.
  • MRI enables accurate and reproducible assessment of cardiovascular anatomy and function.
  • Novel targeted MRI contrast agents allow for molecular imaging within the same session.

Conclusions:

  • Recent advances in MRI technology significantly enhance preclinical cardiovascular research capabilities.
  • MRI provides a powerful, non-invasive tool for studying cardiovascular disease mechanisms and therapeutic efficacy in vivo.
  • Integrated anatomical, functional, and molecular imaging using MRI is transforming cardiovascular disease investigation.