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In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
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Myocardial viability imaging and revascularization in chronic ischemic left ventricular systolic dysfunction

Tanya H Tajouri1, Panithaya Chareonthaitawee

  • 1Department of Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

Expert Review of Cardiovascular Therapy
|December 18, 2009
PubMed

Insights

Noninvasive viability imaging aids decisions for revascularization in patients with moderate-to-severe left ventricular systolic dysfunction. Current techniques offer benefits but require further outcome studies for optimal treatment strategies.

Area of Science:

  • Cardiology
  • Medical Imaging

Background:

  • Revascularization in moderate-to-severe left ventricular systolic dysfunction carries high risks.
  • Noninvasive viability imaging is crucial for guiding treatment decisions in these patients.

Purpose of the Study:

  • To review the current status of viability imaging techniques.
  • To discuss revascularization strategies in chronic ischemic left ventricular systolic dysfunction.

Main Methods:

  • Review of established and emerging noninvasive viability imaging modalities.
  • Assessment of current evidence on the impact of imaging on patient outcomes.

Main Results:

  • Positron emission tomography (PET), single-photon emission computed tomography (SPECT), and dobutamine echocardiography are established techniques.
  • Cardiac MRI is increasingly used, and computed tomography shows promise.
  • Evidence linking viability imaging to improved patient outcomes is largely from observational studies.

Conclusions:

  • Viability imaging offers advantages and disadvantages across modalities.
  • Optimal treatment strategies for this patient group remain uncertain.
  • Further research is needed to clarify the role of viability imaging in improving patient outcomes.

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