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Acute Coronary Syndrome III: Diagnostic Studies

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Updated: Jun 17, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Published on: February 26, 2013

Left atrial appendage: structure, function, imaging modalities and therapeutic options.

Salima Qamruddin¹, Jerold Shinbane, Jabi Shriki

¹Echocardiography Laboratories, Keck School of Medicine, University of Southern California, 1510, San Pablo Street, Suite 322, Los Angeles, CA 90033, USA.

Expert Review of Cardiovascular Therapy

|December 18, 2009

Summary

This summary is machine-generated.

The left atrial appendage (LAA) is a frequent source of blood clots causing stroke. Detailed imaging is crucial for detecting LAA thrombus and developing new preventative devices.

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Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure

Published on: February 8, 2022

Area of Science:

Cardiology
Medical Imaging

Background:

The left atrial appendage (LAA) is a primary site for cardiac thrombus formation and subsequent systemic embolism.
Its complex, variable anatomy necessitates thorough multi-planar imaging for accurate thrombus evaluation.

Purpose of the Study:

To highlight the importance of comprehensive imaging for left atrial appendage thrombus detection.
To discuss current and advanced imaging modalities for LAA thrombus assessment.
To emphasize the need for novel LAA occluder devices.

Main Methods:

Transesophageal echocardiography (TEE) is the standard imaging modality for ruling out LAA thrombus.
Doppler imaging aids in assessing LAA function.
Advanced techniques including 3D TEE, CT, and MRI offer enhanced thrombus detection and characterization.

Main Results:

Variable LAA anatomy requires multi-plane imaging for complete thrombus assessment.
TEE with Doppler provides essential functional and morphological data.
3D imaging modalities (TEE, CT, MRI) improve thrombus detection and sizing.

Conclusions:

Accurate thrombus detection in the LAA is critical for preventing systemic embolism.
A combination of imaging techniques ensures comprehensive LAA evaluation.
Development of innovative transcatheter LAA occluder devices is essential for LAA-related embolism prevention.