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Updated: Jun 17, 2026
07:28
Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation
Published on: October 11, 2024
Bilateral diffuse pulmonary infiltration in a heart transplant recipient
B Sharif-Kashani1, Z H Ahmadi, B Bikdeli
1Cardiovascular Department, Masih Daneshvari Hospital, Shahid Beheshti University MC, Tehran, Iran.
Summary
Kaposi sarcoma, a vascular tumor, can affect organs after heart transplantation. This case shows successful treatment of pulmonary Kaposi sarcoma with immunosuppression modulation and chemotherapy.
Area of Science:
- Oncology
- Immunology
- Cardiology
Background:
- Pulmonary complications are common after heart transplantation.
- Immunosuppressive therapy is crucial post-transplant but can increase infection and malignancy risks.
- Kaposi sarcoma is a vascular tumor associated with human herpesvirus 8, often seen in immunocompromised individuals.
Observation:
- A heart transplant recipient developed Kaposi sarcoma 6 months post-surgery.
- The patient presented with diffuse bilateral pulmonary infiltration and dyspnea.
- Cutaneous lesions were also noted, indicating widespread disease.
Findings:
- Visceral and cutaneous Kaposi sarcoma occurred in an immunocompromised heart transplant patient.
- Pulmonary infiltration was a significant manifestation of the disease.
- The condition was diagnosed 6 months after heart transplantation.
Implications:
- Early diagnosis and intervention are critical for managing Kaposi sarcoma in transplant recipients.
- Modulating immunosuppression and utilizing chemotherapy can lead to favorable outcomes.
- This case highlights the importance of vigilance for opportunistic infections and malignancies post-transplant.
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