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Related Experiment Video

Updated: Jun 17, 2026

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists

Published on: July 11, 2025

Iatrogenic perforation at colonic imaging.

J S Khan¹, B J Moran

¹Queen Alexandra Hospital, Portsmouth, UK. mkhan207@aol.com

Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland

|December 18, 2009

Summary

This summary is machine-generated.

Colonic imaging procedures like endoscopy, barium enema, and CT colonography (CTC) carry a low risk of iatrogenic perforation. Awareness and prompt management of these rare complications are crucial for patient safety.

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Last Updated: Jun 17, 2026

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists

Published on: July 11, 2025

Area of Science:

Gastroenterology
Radiology
Surgical Complications

Background:

Colonic imaging is essential for colorectal cancer diagnosis and screening.
Current methods like endoscopy, barium enema, and CT colonography (CTC) carry inherent risks, including perforation.
Balancing the benefits of imaging against potential complications is critical.

Purpose of the Study:

To review the literature on the incidence, presentation, and management of iatrogenic colonic perforation.
To assess the risk of perforation associated with different colonic imaging modalities.

Main Methods:

A comprehensive literature review was conducted using PubMed, Cochrane library, and personal archives.
Manual cross-referencing and review of relevant studies reporting complications were performed.
Studies detailing complications of endoscopy, barium enema, and CT colonography were included.

Main Results:

Colonoscopy data from 24 studies (640,433 procedures) showed 585 iatrogenic perforations (0.06%).
Double-contrast barium enema had a reported perforation rate between 0.02% and 0.24%.
CT colonography (CTC) reported nine perforations in 24,365 patients (0.036%), with infrequent serious complications.

Conclusions:

Iatrogenic colonic perforation is an infrequent complication across all imaging modalities, likely under-reported.
Maintaining awareness of perforation risks is essential.
Early diagnosis and active management of iatrogenic perforation are key to minimizing adverse outcomes.