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Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
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Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
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Updated: Jun 17, 2026

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
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Published on: February 17, 2018

Saw-tooth cardiomyopathy.

Periklis A Davlouros1, Peter G Danias, Ageliki A Karatza

  • 1Cardiology Department, Patras University Hospital, Rion, Greece. pdav@otenet.gr

Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance
|December 18, 2009
PubMed
Summary
This summary is machine-generated.

A rare form of infant cardiomyopathy, termed saw-tooth cardiomyopathy, features unique myocardial projections. This condition presents with left ventricular dysplasia and mild systolic dysfunction in infants.

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Area of Science:

  • Pediatric Cardiology
  • Cardiovascular Imaging
  • Congenital Heart Disease

Background:

  • Cardiomyopathy in infants can manifest in various forms.
  • Early diagnosis and characterization are crucial for appropriate management.
  • Left ventricular dysplasia is a rare congenital anomaly.

Observation:

  • A two-month-old infant presented with a grade-I systolic murmur.
  • Echocardiography revealed left ventricular (LV) dysplasia with saw-tooth-like myocardial projections.
  • Cardiovascular magnetic resonance confirmed these projections and showed LV hypokinesis.

Findings:

  • The infant exhibited characteristic saw-tooth-like inward myocardial projections from the LV lateral walls.
  • Mild LV systolic dysfunction and apical hypokinesia were observed.
  • Imaging showed projections from the interventricular septum and lateral wall without late gadolinium enhancement.

Implications:

  • This case introduces 'saw-tooth cardiomyopathy' as a distinct entity.
  • Understanding this rare condition aids in differential diagnosis of infant cardiomyopathies.
  • Further research may elucidate the etiology and long-term prognosis of saw-tooth cardiomyopathy.