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Related Concept Videos

Obsessive-Compulsive Disorder01:28

Obsessive-Compulsive Disorder

Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...
Personality Disorders: Dependent and Obsessive-Compulsive01:24

Personality Disorders: Dependent and Obsessive-Compulsive

Dependent personality disorder and obsessive-compulsive personality disorder are two separate psychological conditions that influence behavior, relationships, and overall life functioning. Though both involve maladaptive behaviors, their core characteristics and motivations differ significantly.
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Observational Studies01:11

Observational Studies

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Introspection01:29

Introspection

Introspection, long upheld as a reliable route to self-knowledge, involves examining one's thoughts, emotions, and mental processes. It underpins many psychological practices, from mindfulness meditation to psychotherapy and self-help strategies. However, empirical evidence challenges the accuracy of introspection as a means of understanding oneself.Limitations of Introspective InsightSeminal work by Nisbett and Wilson demonstrated that individuals are frequently unaware of the true causes...
Panic Disorder01:27

Panic Disorder

Panic disorder is an anxiety disorder characterized by recurrent and sudden minutes-long episodes of intense fear, known as panic attacks. These attacks may feel like heart attacks and often happen without warning or a specific cause. They can include symptoms such as rapid heart rate, shortness of breath, chest pain, trembling, sweating, dizziness, and a sense of helplessness. During a panic attack, individuals may feel as though they are experiencing a heart attack or are in a...
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Paranoid Personality Disorder
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Related Experiment Video

Updated: Jun 17, 2026

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
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Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

Obsessive-compulsive disorder with poor insight: a three-year prospective study.

Francesco Catapano1, Francesco Perris, Michele Fabrazzo

  • 1Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, I-80138 Naples, Italy. francesco.catapano@unina2.it

Progress in Neuro-Psychopharmacology & Biological Psychiatry
|December 18, 2009
PubMed
Summary

Poor insight in obsessive-compulsive disorder (OCD) patients indicates a more severe condition with complex symptoms and poorer treatment outcomes. This subgroup requires specialized management strategies for better prognosis.

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Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
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Last Updated: Jun 17, 2026

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
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Published on: March 14, 2025

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
09:29

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Published on: January 9, 2015

Area of Science:

  • Psychiatry
  • Clinical Psychology

Background:

  • Evidence on poor insight in obsessive-compulsive disorder (OCD) is conflicting.
  • Limited data exists on the long-term course and treatment outcomes for OCD patients with poor insight.

Purpose of the Study:

  • To investigate the clinical characteristics, long-term course, and treatment outcomes of OCD patients with poor insight.
  • To identify if poor insight specifier helps define a distinct subgroup of OCD patients.

Main Methods:

  • A prospective study of 106 outpatients diagnosed with OCD.
  • Insight assessed using the Brown Assessment of Beliefs Scale (BABS).
  • Patients followed for 3 years with systematic psychopathology evaluations.

Main Results:

  • Poor insight OCD patients (22%) exhibited greater symptom severity, earlier onset, and higher rates of familial schizophrenia spectrum disorder and schizotypal personality disorder.
  • These patients were less likely to achieve remission, required more treatment trials, and more frequently received antipsychotic augmentation.
  • Poor insight identified a subgroup with complex presentation, diminished response to standard treatment, and poorer prognosis.

Conclusions:

  • The "poor insight" specifier identifies a more severe OCD subgroup.
  • This subgroup has a complex clinical profile and a less favorable treatment response.
  • Further research is needed for effective management strategies for this patient group.