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Arteries of the Head and Neck

Arteries of the Head and Neck

The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...

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High-Speed Human Temporal Bone Sectioning for the Assessment of COVID-19-Associated Middle Ear Pathology

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Polyarteritis nodosa: a human temporal bone study.

Shruti Joglekar¹, Armin Farajzadeh Deroee, Norimasa Morita

¹Otitis Media Research Center, Department of Otolaryngology, University of Minnesota, Minneapolis, MN 55455, USA.

American Journal of Otolaryngology

|December 18, 2009

Summary

This summary is machine-generated.

Polyarteritis nodosa can cause significant temporal bone changes, including otitis media and inner ear vasculitis, potentially leading to hearing loss. This study highlights the link between this vasculitis and cochlear damage.

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An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

Published on: February 8, 2019

Area of Science:

Otopathology
Vascular Inflammation
Histopathology

Background:

Polyarteritis nodosa is a systemic vasculitis affecting multiple organs.
Hearing loss can be an initial symptom of polyarteritis nodosa.
Temporal bone evaluation is crucial for understanding otologic manifestations.

Observation:

A retrospective analysis of 5 human temporal bones from 3 patients with confirmed polyarteritis nodosa was conducted.
Histopathological examination revealed generalized vasculitis affecting small and medium-sized arteries.
Otologic findings included chronic and serous otitis media, middle ear arteritis, and labyrinthine artery vasculitis.

Findings:

Two out of three patients presented with hearing loss; one also had facial palsy.
Histopathology showed damage to the organ of Corti and spiral ganglion cells in 4 temporal bones.
Fibrosis, osteogenesis, and vasculitis were observed in the middle and inner ear structures.

Implications:

Polyarteritis nodosa leads to significant temporal bone pathology, including otitis media and cochlear damage.
Inner ear vasculitis is associated with sensorineural hearing loss in polyarteritis nodosa.
Histopathological findings correlate with otologic symptoms, aiding diagnosis and management.