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Related Concept Videos

Deglutition01:25

Deglutition

Swallowing, otherwise known as deglutition, facilitates the transport of food from the mouth to the stomach. It is a multifaceted process that involves both the tongue and the muscles of the throat and esophagus. Saliva and mucus aid in this process, which takes approximately 4 to 8 seconds for semi-solid or solid food and around 1 second for liquids or very soft food.
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Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
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Related Experiment Video

Updated: Jun 17, 2026

Method of Studying Palatal Fusion using Static Organ Culture
04:58

Method of Studying Palatal Fusion using Static Organ Culture

Published on: September 19, 2015

Micromanaging Palate Development.

David E Clouthier1, Josie Gray, Kristin Bruk Artinger

  • 1Department of Craniofacial Biology, University of Colorado Denver, Aurora, CO 80045, USA.

Perspectives on Speech Science and Orofacial Disorders
|December 18, 2009
PubMed
Summary
This summary is machine-generated.

Neural crest cells form facial structures and the palate through intricate developmental processes. MicroRNAs, a type of small non-coding RNA, are newly identified regulators of palate development and potential therapeutic targets for birth defects.

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Last Updated: Jun 17, 2026

Method of Studying Palatal Fusion using Static Organ Culture
04:58

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Published on: September 19, 2015

Isolation and Time-Lapse Imaging of Primary Mouse Embryonic Palatal Mesenchyme Cells to Analyze Collective Movement Attributes
07:13

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Published on: February 13, 2021

Live Imaging of Mouse Secondary Palate Fusion
06:10

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Published on: July 27, 2017

Area of Science:

  • Developmental biology
  • Craniofacial development
  • Molecular biology

Background:

  • Facial skeleton and neck structures develop from neural crest cells.
  • Palatogenesis, or palate formation, involves similar developmental processes.
  • Understanding these processes is crucial for addressing craniofacial birth defects.

Purpose of the Study:

  • To review the embryology of palate formation.
  • To discuss mechanisms causing palatal dysmorphologies.
  • To highlight the role of microRNAs in palate development.

Main Methods:

  • Review of existing literature on craniofacial and palatal development.
  • Analysis of gene regulation in neural crest cell development.
  • Examination of microRNA involvement in cellular development.

Main Results:

  • Neural crest cell migration and differentiation are key to facial and palatal development.
  • Dysregulation of developmental pathways can lead to palatal abnormalities.
  • MicroRNAs represent a novel regulatory layer in palatogenesis.

Conclusions:

  • Palate development is a complex process recapitulating facial development.
  • MicroRNAs offer new insights into the regulation of palatogenesis.
  • MicroRNAs may serve as targets for treating congenital palatal defects.