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Updated: Jun 17, 2026
13:22
Adhesion Frequency Assay for In Situ Kinetics Analysis of Cross-Junctional Molecular Interactions at the Cell-Cell Interface
Published on: November 2, 2011
A review of adhesion science
Sally J Marshall1, Stephen C Bayne, Robert Baier
1University of California, San Francisco, S/D Preventive & Restorative Dental Science, 707 Parnassus Avenue, San Francisco, CA 94141-0758, USA. sally.marshall@ucsf.edu
Summary
Understanding adhesive joints requires focusing on interface science. Key principles for strong bonds include surface cleanliness, roughness, wetting, and proper curing for reliable material performance.
Area of Science:
- Materials Science
- Surface Science
- Adhesion Science
Background:
- Adhesive joints consist of adherends, adhesives, and interfaces.
- Adhesion science investigates interface formation, evolution, and failure.
- Adhesive joints can involve multiple interfaces.
Purpose of the Study:
- To understand the critical factors governing the formation and performance of adhesive interfaces.
- To highlight the importance of interface characterization in adhesion science.
Main Methods:
- Focus on principles for good interface formation: surface cleanliness, roughness, wetting, flow, and curing.
- Utilize advanced characterization techniques for interface analysis.
Main Results:
- Successful bonding relies on micro-mechanical interactions, alongside physical, chemical, and mechanical contributions.
- Interface characterization before, during, and after service is crucial but challenging.
Conclusions:
- Rigorous application of techniques like comprehensive contact angle analysis for surface energy and Atomic Force Microscopy (AFM) alongside Scanning Electron Microscopy (SEM) for surface texture is recommended.
- Further research is needed to assess interface energetics and properties over time and under various conditions.
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01:14Adhesion
Adhesion occurs when one type of molecule is attracted to a different molecule. Water exhibits adhesive properties in the presence of polar surfaces, such as glass or cellulose in plants. For instance, when water is poured into a glass, the positively charged hydrogen molecules of water are more attracted to the negatively charged oxygen molecules in the silica than to the oxygen in neighboring water molecules.
Capillary action is a result of water’s adhesive tendencies. When a narrow glass...
Capillary action is a result of water’s adhesive tendencies. When a narrow glass...
01:14Cell Adhesion in Plants
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01:20Cell Adhesion Molecules - Types and Functions
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