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Disposable Dosators Intended for Dry Powder Delivery to Mice
Published on: August 18, 2023
The use of dry powder inhaler devices by elderly patients suffering from chronic obstructive pulmonary disease
P Quinet1, C A Young, F Héritier
1Hôpital Riviera, CTR Riviera, Blonay, Switzerland. pascal.quinet@hopital-riviera.ch
Unlabelled:
Twenty-five COPD patients, aged 65years or above, were recruited to test their ability to use dry powder inhaler Handihaler (Boeringher-Ingelheim) and Aerolizer (Novartis). The results of a score created to evaluate the inhalation technique were compared with age, MMSE, Barthel Index, FEV(1), maximum inspiratory and expiratory pressures, and peak inspiratory flow (PIF).
Results:
Dry powder inhalers were correctly used by 60% of the patients (15 out of 25). Among the capable ones, 13 out of 15 were aged less than 80 years (p< or =0.02), 13 out of 15 had a maximum inspiratory pressure greater or equal to 53cm H(2)O (p< or =0.001) and a PIF greater or equal to 120l/min (p< or =0.05). All skilled patients had a minimum MMSE of 25 (p< or =0.001).
Conclusion:
In a geriatric population, age, the decrease of maximum inspiratory pressure and PIF as well as cognitive functions, limit the use of dry powder inhalers.
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