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Updated: Jun 17, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
Update on the treatment of saphenous reflux: laser, RFA or foam?
Kellie Brown1, Colleen J Moore
1Medical College of Wisconsin, Milwaukee, WI, USA.
Abstract:
Chronic venous insufficiency resulting from great saphenous vein (GSV) reflux is a problem seen with increasing frequency in most vascular surgical practices. Traditionally treated with high ligation and stripping, minimally invasive techniques for ablation of the GSV have evolved. These include endovenous laser surgery, radiofrequency ablation, and foam sclerotherapy. The authors discuss the mechanism of action of each modality, as well as the techniques for intervention, outcomes, and complications. Minimally invasive treatment of venous insufficiency is efficacious, with less morbidity than high ligation and stripping, allowing for successful treatment and improved patient satisfaction.
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