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Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents01:18

Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents

Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...
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Giardiasis

Giardiasis is a globally prevalent intestinal infection caused by the protozoan parasite Giardia duodenalis (also known as G. lamblia or G. intestinalis). This flagellated protozoan is the most frequently identified intestinal parasite in the United States and worldwide. Transmission primarily occurs via the fecal-oral route, with infection arising from ingestion of water or food contaminated with cysts. Individuals in low-resource settings, international travelers, outdoor enthusiasts, daycare...
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Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
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Cholera

Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...
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Diarrhea is characterized by the occurrence of frequent, watery bowel movements. Various factors can trigger diarrhea, including viral or bacterial infections, foodborne illnesses, side effects from certain medications, and underlying digestive disorders. If not adequately managed, diarrhea can lead to complications such as dehydration, electrolyte imbalances, and nutrient deficiencies. Severe diarrhea can lead to significant weight loss, malnutrition, and weakened immune function.
Adsorbents...
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Related Experiment Video

Updated: Jun 17, 2026

Culture Methods to Determine the Limit of Detection and Survival in Transport Media of Campylobacter Jejuni in Human Fecal Specimens
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Published on: March 10, 2020

Travellers' diarrhea in children.

Pierre J Plourde1

  • 1Winnipeg Regional Health Authority, Winnipeg, Manitoba.

Paediatrics & Child Health
|December 19, 2009
PubMed
Summary

Travellers diarrhea is a common health issue for those visiting developing countries, with young children facing higher risks. Most cases are acute, self-limiting, and occur during or shortly after trips.

Area of Science:

  • Global Health
  • Infectious Diseases
  • Travel Medicine

Background:

  • Travellers diarrhea represents a significant health concern for international travelers, particularly to developing nations.
  • Young children are disproportionately affected, experiencing a higher incidence and more severe outcomes.

Purpose of the Study:

  • To summarize the epidemiology and clinical presentation of travellers diarrhea.
  • To highlight the prevalence and risk factors associated with this common travel-related illness.

Main Methods:

  • Review of existing literature on travellers diarrhea.
  • Analysis of epidemiological data regarding affected populations and risk factors.

Main Results:

  • Up to 50% of travelers to developing countries experience acute diarrhea during a two-week trip.
Keywords:
ChildrenTravellers’ diarrhea

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Culture Methods to Determine the Limit of Detection and Survival in Transport Media of Campylobacter Jejuni in Human Fecal Specimens
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  • Episodes typically manifest abruptly during travel or upon return and are generally self-limiting.
  • Conclusions:

    • Travellers diarrhea is a widespread issue with a notable impact on travelers, especially children.
    • Understanding the incidence and self-limiting nature of the condition is crucial for traveler health management.