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A case of cellulitis causing tissue defect during etanercept therapy

Dulgeroglu Deniz1, Umay Ebru, Bal Ajda

  • 1Department of Physical Therapy and Rehabilitation, Ankara Diskapi Yildirim Beyazit Education and Research Hospital, Ministry of Health, Huzur mah 1157. sok 13-1/11 Dikmen Ankara Turkey, Ankara, Turkey. denizdulgeroglu@gmail.com

Rheumatology International
|December 19, 2009
PubMed

Tumor necrosis factor-alpha (TNF-α) antagonists are employed increasingly during recent years in patients with active rheumatoid arthritis who do not respond to disease-modifying anti-rheumatic drugs. Contraindications such as infections, auto-antibody formation and hypersensitive reactions can be observed during the treatment with TNF-α antagonist drugs. Our case was a 52-year-old woman, followed by several centers for a period of 21 years with a seropositive, erosive and nodular RA diagnosis. Anti TNF-α treatment was commenced due to the failure to control the disease. During the treatment, a serious cellulite developed, which required hospitalization and surgical debridement as well as intravenous antibiotics treatment. Through the present case, we aimed to draw attention to the skin infection during the use of etanercept in a patient with RA.

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