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Ocular growth and morbidity in preterm children without retinopathy of prematurity

Murat Özdemir1, Sedat Koylu2

  • 1Department of Ophthalmology, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaras, 46100, Turkey. drmozdemir@hotmail.com.

Japanese Journal of Ophthalmology
|December 19, 2009
PubMed

Insights

Premature birth without retinopathy of prematurity (ROP) is linked to longer eye growth, but not significant refractive errors. However, conditions like strabismus and amblyopia may be more common in these children.

Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Developmental Biology

Background:

  • Premature birth is a significant risk factor for various ocular abnormalities.
  • Retinopathy of prematurity (ROP) is a well-known complication, but ocular outcomes in preterm infants without ROP require further investigation.

Purpose of the Study:

  • To investigate ocular growth and associated morbidities in preschool and school-aged children born prematurely but without a history of ROP.
  • To determine if prematurity influences refractive errors and other visual functions in children without ROP.

Main Methods:

  • A population-based study involving 26 children (5-7 years old) born prematurely without ROP.
  • Comprehensive ocular examinations including visual acuity, cycloplegic refraction, color vision, ocular alignment, and anterior/posterior segment assessments.
  • Measurements of anterior chamber depth, lens thickness, vitreous length, and total axial length.

Main Results:

  • No correlation was found between the degree of prematurity and visual acuity or refractive state.
  • Prevalence of strabismus (7.7%), amblyopia (7.7%), and anisometropia (15%) was noted.
  • Total axial length and vitreous length showed significant positive correlations with gestational age and birth weight.

Conclusions:

  • Increased ocular axial and vitreous length in preterm children without ROP, correlating with gestational age and birth weight, does not lead to significant refractive errors.
  • Preterm children without ROP may have a higher prevalence of strabismus, amblyopia, and anisometropia compared to normally delivered children.
Abstract

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