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Related Experiment Video

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Testing Tactile Masking between the Forearms

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Published on: February 10, 2016

Masking and manipulation.

Rosa Ventura¹, Jordi Segura

¹Institut Municipal d'Investigació Mèdica IMIM-Hospital del Mar, Av. Dr. Aiguader 88, 08003 Barcelona, Spain.

Handbook of Experimental Pharmacology

|December 19, 2009

Summary

This summary is machine-generated.

This study reviews masking agents in sports doping, including diuretics, probenecid, 5alpha-reductase inhibitors, plasma expanders, and epitestosterone. It discusses their pharmacological actions, doping effects, metabolism, and detection methods for anti-doping controls.

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Area of Science:

Sports Science
Pharmacology
Analytical Chemistry

Background:

Masking agents are prohibited substances in sports doping.
These agents are used to conceal the use of other performance-enhancing drugs.
They are banned in both in- and out-of-competition doping tests.

Purpose of the Study:

To review the pharmacological actions of various masking agents.
To discuss their intended effects for doping purposes.
To cover their biotransformation and analytical detection methods in anti-doping controls.

Main Methods:

Literature review of pharmacological data.
Analysis of biotransformation pathways.
Discussion of analytical procedures for detection.

Main Results:

Detailed pharmacological profiles of diuretics, probenecid, 5alpha-reductase inhibitors, plasma expanders, and epitestosterone.
Explanation of how each agent masks other doping substances.
Overview of analytical techniques for screening and confirmation.

Conclusions:

Understanding masking agents is crucial for effective anti-doping strategies.
Comprehensive knowledge of their pharmacology and detection is essential for sports integrity.
Analytical methods must continuously evolve to counter the misuse of these substances.