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Related Concept Videos

Fetal Circulation01:14

Fetal Circulation

Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...

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Updated: Jun 17, 2026

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators
09:51

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators

Published on: March 21, 2018

Profiling fetal cardiac function in twin-twin transfusion syndrome.

J J Stirnemann1, M Mougeot, F Proulx

  • 1Department of Obstetrics and Gynecology, GHU Necker Enfants Malades, University Paris Descartes, Paris, France.

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
|December 19, 2009
PubMed
Summary

Assessing recipient twin cardiac function in twin-twin transfusion syndrome (TTTS) quantitatively identifies cardiomyopathy. This cardiac profiling aids in disease staging, distinguishing cases with myocardial dysfunction when laser coagulation is the primary treatment.

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Published on: September 5, 2011

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Last Updated: Jun 17, 2026

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators
09:51

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators

Published on: March 21, 2018

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas
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Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas

Published on: September 5, 2011

Area of Science:

  • Fetal Medicine
  • Cardiology
  • Perinatology

Background:

  • Cardiomyopathy in the recipient twin is a key indicator of twin-twin transfusion syndrome (TTTS) severity.
  • Quantitative assessment of cardiac function may improve disease staging and management.

Purpose of the Study:

  • To quantitatively describe cardiac function in the recipient twin of TTTS pregnancies.
  • To evaluate the predictive value of preoperative cardiac function profiles for perinatal outcomes.
  • To compare identified cardiac profiles with the Quintero staging system.

Main Methods:

  • Fetal echocardiography was performed before laser coagulation in monochorionic pregnancies with TTTS.
  • Unsupervised classification analysis identified distinct cardiac function profiles in recipient twins.
  • Perinatal death was used as the primary outcome to assess predictive value.

Main Results:

  • Three preoperative cardiac profiles were identified, reflecting progressive cardiomyopathy.
  • No significant correlation was found between cardiac profiles and pregnancy outcomes.
  • 55% of Quintero Stage 1 cases exhibited significant recipient twin cardiac dysfunction.

Conclusions:

  • Quantitative cardiac profiling in the recipient twin can assess progressive cardiomyopathy in TTTS.
  • Cardiac profiling aids in identifying significant myocardial dysfunction, surpassing current staging methods.
  • When fetoscopic laser coagulation is the first-line treatment, cardiomyopathy assessment does not impact pregnancy outcome.