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In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis
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[Kinetic features of ascites and solid Ehrlich tumors]
Voprosy Onkologii
|December 22, 2009
Abstract:
Such biological parameters as tumor volume, Ki-67 and p53, which characterize the development of ascites and solid tumor of Ehrlich were evaluated. The kinetic curve of growth of ascites tumor was S-shaped (Gomperts) while that of the solid one--cubic (Speer-Retsky). Ki-67 expression level was found to be in cyclic correlation with duration (3 and 6 day intervals) which might be worth considering when working out therapeutic procedure. Moreover, no increase in cell death was observed when tumor growth slowed down.
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