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Soft tissue calcifications induced by local corticosteroid injection.

R J Conti1, M Shinder

  • 1Department of Podiatric Surgery Metropolitan Hospital, Philadelphia, Pennsylvania.

The Journal of Foot Surgery
|January 1, 1991
PubMed
Summary
This summary is machine-generated.

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Local corticosteroid injections, like triamcinolone hexacetonide, may cause soft tissue calcifications. This can occur when insoluble steroid accumulates, leading to inflammation and calcification in the heel.

Area of Science:

  • Orthopedics
  • Dermatology
  • Pharmacology

Background:

  • Local corticosteroid injections are commonly used for inflammatory conditions.
  • Heel spur syndrome is a frequent indication for corticosteroid therapy.
  • Potential adverse effects of local injections require ongoing investigation.

Observation:

  • A case report details soft tissue calcifications in the heel.
  • The patient received multiple injections of triamcinolone hexacetonide for heel spur syndrome.
  • Imaging revealed significant calcific deposits in the affected soft tissues.

Findings:

  • Accumulation of insoluble triamcinolone hexacetonide acted as a foreign body.
  • This led to a chronic granulomatous inflammatory response.

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  • Dystrophic calcification developed secondary to the chronic inflammation.

    • Implications:

    • Clinicians should be aware of soft tissue calcification as a potential complication of local corticosteroid therapy.
    • Consideration of alternative treatments or injection techniques may be warranted in certain cases.
    • Further research is needed to elucidate the exact mechanisms and prevalence of this adverse effect.