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Sleep-disordered breathing symptoms frequency and growth among prematurely born infants
Hawley E Montgomery-Downs1, Marion E Young, Miriam A Ross
1West Virginia University, Department of Psychology, Morgantown, WV 26506-6040, USA. Hawley.Montgomery-Downs@mail.wvu.edu
Insights
Sleep-disordered breathing (SDB) symptoms are common in preterm infants and linked to lower weight. Early identification of risk factors and treatments is crucial for these vulnerable infants.
Area of Science:
- Pediatric Sleep Medicine
- Neonatology
- Developmental Pediatrics
Background:
- Infants born prematurely face increased risks for sleep-disordered breathing (SDB) compared to full-term infants.
- SDB can have significant impacts on infant health and development.
Purpose of the Study:
- To determine the frequency of SDB symptoms in preterm infants.
- To evaluate the effects of SDB on infant growth.
- To identify risk factors for SDB in this population to guide prevention and early intervention.
Main Methods:
- The Louisville pediatric SDB risk survey was used.
- Primary caretakers of preterm infants at a Neonatal Follow-Up Clinic participated.
- 173 infants were assessed at a corrected age of 9.13 months.
Main Results:
- 8.1% of preterm infants snored ≥3 days/week, indicating SDB.
- Higher SDB symptom scores correlated with lower weight-for-age percentiles (r=-.18, p=.028).
- Birth weight and size for gestational age did not correlate with SDB risk.
Conclusions:
- SDB symptoms are present in infants born preterm.
- SDB in preterm infants is associated with impaired growth.
- Further research on SDB natural history, risk factors, and treatments is essential.
Background:
Children who were born prematurely are at higher risk for sleep-disordered breathing (SDB) compared to their same-age peers who were born fullterm.
Objective:
The objective of the present study was to assess the frequency of SDB symptoms and effects on growth among preterm infants while they are still infants, with a goal of identifying risk factors to facilitate prevention and early intervention.
Methods:
The Louisville pediatric SDB risk survey was administered to the primary caretakers of prematurely born infants attending the Neonatal Follow-Up Clinic at West Virginia University Children's Hospital.
Results:
Participation was 100% among 173 consecutive patients invited to participate in the study. At 9.13 months corrected age, 8.1% of infants born at a mean of 31.6 weeks gestation were reported to snore > or = 3 days/week, a rate consistent with diagnosis of sleep-disordered breathing among older children. A composite of nine parent-reported symptoms was created based on factor analysis. Birth weight and size for gestational age at birth did not differ between snoring groups or correlate with the composite score. But a significant negative correlation between the composite risk for SDB score and current weight for adjusted age percentile score indicate that infants with higher SDB symptom profiles have lower weight for age (r=-.18, p=.028).
Conclusions:
SDB symptoms are detectable among infants born preterm, while they are still infants. Because of their preferential risk for SDB and its somatic consequences, a primary research goal should be description of the natural history of SDB and identification of modifiable risk factors and treatment options.
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