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Updated: Jun 17, 2026

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
Published on: February 16, 2018
Synthesis of dihydrodehydrodiconiferyl alcohol: the revised structure of lawsonicin
Junxiu Meng1, Tao Jiang, Huma Aslam Bhatti
1School of Chemistry, University of Southampton, UK.
Abstract:
Structural revision of lawsonicin, a natural product of Lawsonia alba, is reported based upon comparison of its spectral data with that of the naturally occurring dihydrobenzo[b]furan neolignan (rac)-trans-dihydrodehydrodiconiferyl alcohol, which is found to be identical. A concise synthesis of dihydrodehydrodiconiferyl alcohol, via Rh(2)[S-DOSP](4)-catalysed intramolecular C-H insertion, is described.
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