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Label-free dual assay of DNA sequences and potassium ions using an aptamer probe and a molecular light switch complex

Min Sun Choi1, Minji Yoon, Jin-Ook Baeg

  • 1Department of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, Korea.

Chemical Communications (Cambridge, England)
|December 22, 2009
PubMed

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...