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Calciphylaxis mimicking penile gangrene: a case report
Tanweer A N Bhatty1, Kamran Riaz
1Department of Surgical Specialities, King Fahad Medical City, Riyadh, Saudi Arabia. naweed55@yahoo.com
Thescientificworldjournal
|December 22, 2009
Summary
Calciphylaxis is a rare, life-threatening skin condition often seen in dialysis patients. It causes painful skin necrosis and eschar formation, primarily on extremities, and can mimic penile gangrene.
Area of Science:
- Nephrology
- Dermatology
- Vascular Medicine
Background:
- Calciphylaxis is a rare, severe systemic disease predominantly affecting patients with end-stage renal disease (ESRD) on dialysis.
- It involves calcification of small blood vessels leading to skin necrosis.
Observation:
- Clinical presentation includes painful, violaceous cutaneous plaques with necrosis and eschar formation, typically on distal extremities like toes and fingers.
- Penile involvement is rare but documented, presenting a diagnostic challenge due to its resemblance to penile gangrene.
Findings:
- Elevated parathyroid hormone (PTH) levels and a high calcium-x-phosphorus product are characteristic laboratory findings.
- Radiological imaging often reveals vascular and soft tissue calcification.
Implications:
- Early recognition and multidisciplinary management are crucial for improving outcomes in calciphylaxis.
- Understanding the urological manifestations of calciphylaxis is important for timely diagnosis and treatment, especially when it mimics penile gangrene.
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