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Updated: Jun 17, 2026

Murine Kidney Transplant Technique
Published on: October 20, 2015
Cutaneous warts in children before and after renal transplantation
Andy Lunn1, Jane Ravenscroft, Alan R Watson
1Children's Renal and Urology Unit, Queens Medical Centre Campus, Nottingham University Hospitals NHS Trust, Nottingham, UK.
Insights
Cutaneous warts are more common in children with chronic kidney disease (CKD) and after organ transplantation. Early information and treatment are crucial for managing these common skin infections in CKD patients.
Area of Science:
- Dermatology
- Nephrology
- Immunology
Background:
- Cutaneous warts affect 3.9-4.9% of UK children.
- Uraemia in chronic kidney disease (CKD) can impair immune function, potentially increasing wart incidence.
- Organ transplant recipients may also experience a higher incidence of warts.
Observation:
- A survey of CKD and renal transplant clinic records identified patients with warts.
- Data collected via questionnaire included wart presence, location, treatment, pain, and emotional upset.
- Nine of 49 (18.4%) pre-transplant patients and 17 of 60 (28.3%) post-transplant patients had current warts.
Findings:
- Wart prevalence was higher in post-transplant patients (28.3%) compared to pre-transplant patients (18.4%).
- Many patients (41) sought primary care for treatment; only five transplant patients saw a dermatologist.
- Most patients reported low pain and emotional upset, except for four adolescents with significant distress.
Implications:
- Cutaneous warts are more prevalent in CKD patients.
- Patients require appropriate information and treatment before and after transplantation.
- While primary care can manage most warts, extensive cases causing distress warrant early dermatology referral.
Abstract:
Cutaneous warts occur in 3.9-4.9% of children in the UK. The incidence is increased in organ transplant recipients and may be increased in patients with chronic kidney disease (CKD), since uraemia reduces the immune system's function. We surveyed the records from our CKD and renal transplant clinic to ensure patients with warts were identified and appropriately treated. Data were collected by questionnaire. The presence of warts, location, treatment, levels of pain and emotional upset were recorded. Nine of 49 (18.4%) pre-transplantation patients (33 male, median age 12.1 years) were currently suffering from warts compared with 17 of 60 (28.3%) post-transplantation patients (34 male, median age 13.9 years). A further 14 pre-transplantation and 16 post-transplantation patients had previously suffered from warts which had resolved. Forty-one patients had sought treatment for warts, mainly from primary care. Five patients, all having received transplants, were seen by a dermatologist. Self-rated levels of pain and emotional upset were generally low, apart from those of four adolescent patients who expressed significant emotional upset. We concluded that cutaneous warts are more common among CKD patients. Appropriate information and treatment are required before and after transplantation. The majority of warts can be treated in primary care, but selected patients with extensive warts that cause distress need early referral for dermatology opinion.
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