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Related Concept Videos

Cells of the Epidermis01:24

Cells of the Epidermis

The epidermis is made of four or five layers of epithelial cells, depending on its location in the body. From deep to superficial, these layers are the stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, and stratum corneum.
The cells in all these layers except the stratum basale are called keratinocytes, a type of cell that manufactures and stores the protein keratin. The keratinocytes in the stratum corneum are dead and regularly slough away, being replaced by cells from...
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
Renewal of Skin Epidermal Stem Cells01:12

Renewal of Skin Epidermal Stem Cells

The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular cells,...
Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
The Skin Microbiota01:27

The Skin Microbiota

The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...

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Related Experiment Video

Updated: Jun 17, 2026

Apparatus for Harvesting Tissue Microcolumns
06:06

Apparatus for Harvesting Tissue Microcolumns

Published on: October 25, 2018

Dermabrasion and microdermabrasion.

Lora Alkhawam1, Murad Alam

  • 1Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.

Facial Plastic Surgery : FPS
|December 22, 2009
PubMed
Summary

Dermabrasion and microdermabrasion are distinct skin resurfacing methods that mechanically remove damaged skin layers to promote healing. While both improve skin appearance, dermabrasion ablates deeper skin layers than microdermabrasion.

Area of Science:

  • Dermatology
  • Aesthetic Medicine

Background:

  • Facial skin aging and damage necessitate effective resurfacing techniques.
  • Mechanical exfoliation methods offer potential for skin rejuvenation.

Purpose of the Study:

  • To differentiate dermabrasion and microdermabrasion techniques.
  • To highlight their distinct mechanisms and clinical relevance in skin resurfacing.

Main Methods:

  • Dermabrasion: Mechanical ablation removing epidermis and penetrating to papillary or reticular dermis.
  • Microdermabrasion: Mechanical exfoliation targeting only the uppermost epidermal layer.

Main Results:

  • Both procedures physically abrade skin to promote reepithelialization.
  • Dermabrasion induces significant remodeling of dermal structural proteins.

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  • Microdermabrasion accelerates the natural skin exfoliation process.

    • Conclusions:

    • Dermabrasion and microdermabrasion are distinct facial resurfacing techniques with varying depths of skin ablation.
    • Both methods can yield significant improvements in skin appearance.
    • Emerging applications may increase the relevance of these procedures for practitioners.