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Updated: Jun 17, 2026

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction
Published on: August 17, 2022
Hybrid ultrasound MRI for improved cardiac imaging and real-time respiration control
David A Feinberg1, Daniel Giese, D Andre Bongers
1Advanced MRI Technologies, Sebastopol, California 95472, USA. david.feinberg@advancedmri.com
Abstract:
A hybridized dual-imaging system combining real-time ultrasound imaging and MRI was utilized for cardiac imaging at 1.5 T and 3 T. The ultrasound scanner with a programmable software interface was connected via computer to the MRI scanner. Electronic noise was eliminated with electromagnetic shielding and grounding to the screen room. At 3 T, real-time prospective motion compensation in dynamic cine cardiac imaging was implemented using B-mode ultrasound imaging. The ultrasound technique avoided drawbacks such as signal saturation or steady-state interruption of the MR navigator gating. At 1.5 T, a low-latency real-time feedback to balanced steady state free precision MR imaging was performed in three normal volunteers. Results showed active tracking of the heart during respiratory motion and improvement in time-averaged cardiovascular images. Future studies can fully exploit the potential of the high-frequency position information provided by the ultrasound system for more advanced applications in real-time organ tracking.
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