Related Experiment Video
Updated: Jun 17, 2026
Biochemical Measurement of Neonatal Hypoxia
Published on: August 24, 2011
Two different tests for total bilirubin in neonates and infants
Shen-Dar Chen1, Chuang-Ming Wang, Wen-Li Lee
1Department of Pediatrics, Chia-Yi Christian Hospital, Chia-Yi City, Taiwan.
Background:
The most readily available methods for testing serum total bilirubin in neonates are the capillary tube-directed optics color method and serum biochemistry. Because inconsistency between these two methods may cause confusion in clinical practice, this study was designed to quantify their differences.
Methods:
In 46 neonates with clinical jaundice, total bilirubin was measured by two different methods, using a nonchemical photometric device and a laboratory analyzer.
Results:
Differences in results between these two methods were statistically significant, especially when total bilirubin level exceeded 15 mg/dL.
Conclusion:
Clinicians should be aware of the differences between the two methods when making decisions in patient care.
Related Concept Videos
01:24Pharmacokinetics in Pediatric Patients: Drug Metabolism
01:30Serum Laboratory Studies, Stool Test, Breath Test
01:26Blood Studies I: ABG and VBG
Arterial Blood Gas (ABG)
Arterial Blood Gas (ABG) studies are crucial for assessing the lungs' ability to supply oxygen and remove carbon dioxide, reflecting the patient's ventilation status. They also help understand the kidneys' capacity to reabsorb or...