Transfer delay and in-hospital mortality of trauma patients in Pakistan

Afrasyab Khan1, Hasnain Zafar, Syed Nadir Naeem

  • 1Section of General Surgery, Department of Surgery, Aga Khan University, Karachi, Pakistan.

Insights

Delays in trauma patient transfer to hospitals in developing countries did not significantly impact in-hospital mortality. This suggests that severely injured patients may not survive long enough to reach care.

Area of Science:

  • Trauma care
  • Emergency medicine
  • Public health in developing countries

Background:

  • Trauma remains a significant cause of death and disability in developing nations.
  • Lack of organized emergency medical services leads to critical delays in patient transfer.
  • These delays can exacerbate complications and worsen patient outcomes.

Purpose of the Study:

  • To evaluate the impact of hospital transfer and pre-hospital delays on trauma patient outcomes.
  • To analyze the relationship between time to treatment and survival rates in trauma patients.
  • To assess mortality and morbidity associated with delayed emergency care in a low-resource setting.

Main Methods:

  • Retrospective analysis of 978 trauma patients admitted to Aga Khan University Hospital (AKUH), Karachi, Pakistan (1998-2005).
  • Data collected from a dedicated Trauma Registry, focusing on time from injury to emergency room (ER) arrival.
  • Statistical analysis to compare outcomes between patients arriving within one hour versus those with longer delays.

Main Results:

  • Only 30.9% of patients arrived at the ER within the critical first hour.
  • The average time from injury to ER arrival was 4.7 hours.
  • No statistically significant difference in in-hospital mortality was observed between early (<1h) and delayed (>1h) arrivals (OR=0.9, 95% CI: 0.6, 1.5).

Conclusions:

  • In settings lacking emergency response systems, delayed transfer to tertiary care does not significantly alter in-hospital trauma mortality.
  • The findings may indicate a self-selection bias, where only patients with less severe injuries survive the prolonged transfer times.
  • Further research is needed to optimize pre-hospital trauma care and reduce delays in developing countries.
Abstract