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Updated: Jun 17, 2026
A Hydrogel Construct and Fibrin-based Glue Approach to Deliver Therapeutics in a Murine Myocardial Infarction Model.
Published on: June 14, 2015
Repairing of infarcted myocardium using a novel cell patch therapy
Hiroki Yokomuro1, Yukio Ichikawa, Noritsugu Shiono
1Department of Cardiovascular Surgery, Kanagawa Cardiovascular and Respiratory Centre, Yokohama, Japan. h.yokomuro@chic.ocn.ne.jp
Abstract:
A 54-year-old man underwent left anterior descending artery bypass grafting with cell patch therapy for myocardial infarction. We applied a novel approach to replicating the infarcted myocardium by anchoring polyglycolic acid felt seeded with autologous peripheral blood mononuclear cells in front of the infarcted area. The cell patch remained fixed to the myocardium for 1 month, and the infarcted myocardium was reperfused.
