Related Experiment Video
Updated: Jun 17, 2026
Intra-Operative Neural Monitoring of Thyroid Surgery in a Porcine Model
Published on: February 11, 2019
Intraoperative laryngeal nerve monitoring during thyroidectomy
Kimberly A Donnellan1, Karen T Pitman, C Ron Cannon
1Department of Otolaryngology-Head and Neck Surgery, University of Mississippi Medical Center, 2500 N State Street, Jackson, MS 39216, USA. kdonnellan@ent.umsmed.edu
Objective:
To determine whether nerve integrity monitor testing during thyroidectomy predicts recurrent laryngeal nerve (RLN) function after surgery.
Design:
Prospective cohort outcomes study
Patients:
The study included 210 consecutive patients with thyroid abnormalities who underwent thyroidectomy.
Methods:
All patients were intraoperatively monitored with a nerve integrity monitoring system (Xomed NIM II; Medtronic Inc, Fridley, Minnesota), and their vocal cord function was assessed with fiberoptic laryngoscopy before and after surgery. Normal and impaired vocal cord function were compared using an independent t test with respect to postoperative vocal cord mobility, length of the RLN dissection, and the minimum stimulus needed to generate a response at the completion of surgery.
Results:
There was a statistically significant difference between the stimulus in milliamperes required to stimulate normal vs abnormal functioning nerves at the completion of the procedure at the cricoarytenoid joint (P = .02) and at the distal end of the RLN dissection (P < .01). A greater length of dissected nerve was associated with normal vocal cord function; however, it was not statistically significant (P = .07).
Conclusion:
These data suggest that an RLN that responds at lower-intensity stimulation (
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