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Diagnosing coronary artery disease in women: an update on cardiac imaging modalities
Sheldon E Litwin1, Tiffany C Priester
1From the Cardiology Division, University of Utah, Salt Lake City, Utah.
Insights
Diagnosing coronary heart disease (CHD) in women presents unique challenges. Newer imaging techniques offer improved accuracy for identifying CHD in women, aiding timely treatment.
Area of Science:
- Cardiology
- Women's Health
- Diagnostic Imaging
Background:
- Coronary heart disease (CHD) is the leading cause of mortality in women.
- Diagnosis of CHD in women is complicated by lower perceived risk, atypical symptoms, and lower accuracy of traditional stress tests.
- Many women without obstructive CHD on angiography experience recurrent chest pain.
Purpose of the Study:
- To provide an overview of conventional diagnostic tests for CHD in women.
- To compare the diagnostic accuracy of newer imaging modalities with traditional tests.
- To guide healthcare providers in selecting optimal diagnostic tests for female patients.
Main Methods:
- Review of conventional diagnostic tests for coronary heart disease.
- Evaluation of newer imaging modalities like cardiac computed tomography and magnetic resonance imaging.
- Comparison of diagnostic accuracy and clinical utility of various testing options in women.
Main Results:
- Traditional stress tests show lower accuracy in women compared to men.
- Women have a lower frequency of obstructive CHD detected by angiography.
- Newer imaging modalities demonstrate high diagnostic accuracy, speed, and convenience for CHD assessment in women.
Conclusions:
- Accurate diagnosis of CHD in women is crucial for appropriate management.
- Advanced imaging techniques offer significant advantages in diagnosing CHD in the female population.
- Appropriate test selection enables accurate risk stratification and targeted therapy for women with or at risk for CHD.
Abstract:
Coronary heart disease (CHD) remains the leading cause of death in women. However, there are multiple challenges to the diagnosis of CHD in women, including: 1) women perceive their risk of CHD to be lower than it truly is, 2) women frequently present with atypical cardiac symptoms, 3) traditional stress tests have lower accuracy in women than in men, 4) women have a lower frequency of obstructive CHD detected at angiography than do men, and 5) a high percentage of women without obstructive CHD by invasive angiography have recurrent chest pain. Given the increasing number of options and complexity of noninvasive testing for CHD, it is important for women's health care providers to select the best test for a given patient. Newer imaging modalities such as cardiac computed tomography and magnetic resonance imaging offer speed, convenience, and high diagnostic accuracy in women. The goal of this article is to provide practitioners with an overview of the conventional diagnostic tests and to compare these with the newer imaging modalities. The appropriate application of diagnostic tests should allow practitioners to identify accurately and reassure those patients who are at low risk while targeting those who have preclinical or symptomatic atherosclerosis so that they can receive aggressive medical therapy, referral to cardiovascular specialists, or both.
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