[Adult pertussis poses a severe risk for infants]

Ellen Bamberger1, Gilad Spiegel, David Greenberg

  • 1The Pediatric Department and Clinical Microbiology Laboratory, Bnai Zion Medical Center.

Harefuah
|December 24, 2009
PubMed

Insights

Parental transmission of Bordetella pertussis (whooping cough) is a risk to infants in Israel. Implementing infection control and screening parents can prevent infant pertussis cases.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Epidemiology

Context:

  • Rising Bordetella pertussis (whooping cough) incidence in adolescents and adults in Israel.
  • Infants face the highest risk of pertussis complications and mortality.
  • Hospital settings present potential transmission pathways.

Purpose:

  • To report cases of likely parent-to-infant pertussis transmission in Israeli hospitals.
  • To highlight the importance of considering adult and adolescent carriers in infant pertussis epidemiology.
  • To evaluate the risk of nosocomial pertussis transmission from caregivers.

Summary:

  • Four cases of probable pertussis transmission from parents to their infants occurred in two Israeli hospitals.
  • The findings suggest that healthcare facilities should be vigilant for pertussis in caregivers of infants.
  • Adults and adolescents may serve as reservoirs for Bordetella pertussis, posing a threat to vulnerable infants.

Impact:

  • Recommends enhanced infection control measures in healthcare settings to prevent pertussis spread.
  • Suggests targeted screening of parents and caregivers for pertussis symptoms.
  • Aims to reduce infant morbidity and mortality associated with Bordetella pertussis.

Related Concept Videos

Transmission-based Precautions II: Airborne and Protective Environment01:25

Transmission-based Precautions II: Airborne and Protective Environment

Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia I: Introduction01:29

Pneumonia I: Introduction

Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...
Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics01:23

Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics

Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla.  Benzonatate operates peripherally within the respiratory tract by anesthetizing...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...