Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Underestimation of Intraocular Pressure (IOP) After LASIK and PRK: Systematic Review and Meta-Analysis.

Journal of clinical medicine·2026

Same author

A Novel Rescue Surgical Technique for Stabilization of Scleral-Fixated FIL SSF Intraocular Lens (Carlevale Lens): A Case Report.

Case reports in ophthalmology·2025

Same author

Contralateral Randomized Comparison Between Intracameral Extended-Release Dexamethasone 9% Suspension Placed in the Capsular Bag with the Established Post-Cataract Regimen.

Advances in therapy·2025

Same author

Impact of Microkeratome Dissection Parameters on Textural Interface Opacities in DSAEK Grafts.

Diagnostics (Basel, Switzerland)·2025

Same author

Limbal Stem Cell Deficiency Induced by Prolonged Use of Topical 0.03% Tacrolimus Ointment in a Patient With Atopic Keratoconjunctivitis.

Eye & contact lens·2025

Same author

Allogeneic anterior lens capsule transplantation (ALCT) for the management of HSV neurotrophic keratitis.

American journal of ophthalmology case reports·2025

Search research articles

Related Experiment Video

Updated: Jun 17, 2026

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile

Published on: September 20, 2024

LASIK flap buttonhole treated immediately by PRK with mitomycin C.

George D Kymionis¹, Dimitra M Portaliou, Alexandra E Karavitaki

¹Institute of Vision and Optics, University of Crete, Greece.

Journal of Refractive Surgery (Thorofare, N.J. : 1995)

|December 24, 2009

Summary

Immediate photorefractive keratectomy (PRK) with mitomycin C (MMC) effectively treated LASIK flap buttonholes. This approach restored 20/20 vision and regular topography in all patients within three months.

More Related Videos

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis

Published on: November 12, 2015

An “All-laser” Endothelial Transplant

An “All-laser” Endothelial Transplant

Published on: July 6, 2015

Related Experiment Videos

Last Updated: Jun 17, 2026

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile

Published on: September 20, 2024

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis

Published on: November 12, 2015

An “All-laser” Endothelial Transplant

An “All-laser” Endothelial Transplant

Published on: July 6, 2015

Area of Science:

Ophthalmology
Refractive Surgery
Corneal Surgery

Background:

Laser-Assisted In Situ Keratomileusis (LASIK) is a common refractive surgery.
Complications like LASIK flap buttonholes can occur during the procedure.
Prompt management is crucial to ensure optimal visual outcomes.

Observation:

Three patients experienced LASIK flap buttonholes in the left eye during bilateral LASIK using the SCHWIND Carriazo-Pendula microkeratome.
The buttonhole flaps were repositioned.
Phototherapeutic keratectomy (PTK) for epithelial removal was performed, followed by immediate PRK with topical mitomycin C (MMC) 0.02%.

Findings:

All three patients achieved uncorrected and corrected distance visual acuity of 20/20.
Topographic findings were regular three months post-procedure.
The combined PRK and MMC treatment effectively addressed the LASIK flap buttonhole complication.

Implications:

Immediate PRK with MMC presents a viable and effective treatment strategy for LASIK flap buttonholes.
This technique can restore excellent visual acuity and corneal topography.
It offers a solution to mitigate visual impairment from LASIK flap complications.