Related Experiment Video

Updated: Jun 17, 2026

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
09:52

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis

Published on: March 9, 2018

A rare cause of acute respiratory failure--allergic bronchopulmonary aspergillosis

Ritesh Agarwal, Ashutosh N Aggarwal, Nalini Gupta

    Mycoses
    |December 24, 2009
    PubMed

    Insights

    Allergic bronchopulmonary aspergillosis (ABPA) can present unusually. This case highlights ABPA causing acute hypoxemic respiratory failure due to lung collapse, a previously undocumented presentation.

    Area of Science:

    • Pulmonology
    • Immunology
    • Radiology

    Background:

    • Allergic bronchopulmonary aspergillosis (ABPA) is an immune response to Aspergillus fumigatus, often seen in asthma and cystic fibrosis patients.
    • Common radiological findings include transient opacities, bronchiectasis, and mucoid impaction.

    Observation:

    • A 22-year-old female presented with acute hypoxemic respiratory failure.
    • The patient experienced left lung collapse requiring rigid bronchoscopy.

    Findings:

    • The patient was diagnosed with ABPA.
    • This represents the first reported instance of ABPA presenting as acute hypoxemic respiratory failure secondary to lung collapse.

    Implications:

    • This case expands the spectrum of radiological manifestations of ABPA.
    • Clinicians should consider ABPA in patients with unexplained lung collapse and respiratory failure.
    • Highlights the importance of considering uncommon presentations in diagnosing complex allergic lung diseases.

    More Related Videos

    Open Tracheostomy Gastric Acid Aspiration Murine Model of Acute Lung Injury Results in Maximal Acute Nonlethal Lung Injury09:16

    Open Tracheostomy Gastric Acid Aspiration Murine Model of Acute Lung Injury Results in Maximal Acute Nonlethal Lung Injury

    Published on: February 26, 2017

    Related Concept Videos

    Acute Respiratory Failure-III01:30

    Acute Respiratory Failure-III

    Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without causing...
    Asthma I: Introduction01:28

    Asthma I: Introduction

    Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
    Acute Respiratory Failure-I01:21

    Acute Respiratory Failure-I

    Acute respiratory failure is a condition characterized by the inability of the lungs to perform their primary function: gas exchange. This failure leads to insufficient oxygen levels (hypoxemia) in the blood, elevated carbon dioxide levels (hypercapnia), or both, causing critical impairment in organ function.
    Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
    Acute Respiratory Failure-II01:21

    Acute Respiratory Failure-II

    Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
    The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
    Fungal Phylum Ascomycota01:28

    Fungal Phylum Ascomycota

    Phylum Ascomycota, a major division within the subkingdom Dikarya, comprises a diverse range of fungal species, including both unicellular yeasts and filamentous molds such as Aspergillus and Penicillium. These fungi thrive in a variety of habitats, from aquatic ecosystems to terrestrial environments, playing crucial ecological and economic roles.Morphology and ReproductionThe defining characteristic of Ascomycetes, commonly referred to as sac fungi, is the ascus—a sac-like structure that...
    Atypical Pneumonia01:14

    Atypical Pneumonia

    Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...