Related Experiment Video
Updated: Jun 17, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Cutaneous horn on the upper lip associated with squamous cell carcinoma
Ahmet Islam1, Ilknur Haberal Can, Pervin Dürer
1Department of Otolaryngology, Ankara Training and Research Hospital, Ankara, Turkey. drahmetislam@gmail.com
Abstract:
Cutaneous horn is a protrusion from the skin consisting of cornified material. It usually appears on exposed skin areas especially on the head and neck. A 70-year-old woman applied to our clinic with a hard, conical, black-grey 2 cm lesion on the upper lip. On physical examination, there was no palpable lymph node in the neck other than the lesion. Diagnosed to be cutaneous horn, the lesion was completely removed together with 4-5 mm surrounding tissues under local anaesthesia. The histopathological examination reported this lesion to be cutaneous horn with well differentiated squamous cell carcinoma at its base. No recurrences or metastasis were detected within a follow-up period of 5.5 years. It should be kept in mind that cutaneous horns may be associated with premalignant and malignant lesions at the base, masking numerous conditions.
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Papillary Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
lncRNA - Long Non-coding RNAs

