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Updated: Jun 17, 2026
11:09
Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation
Published on: August 1, 2018
Molecular design of small organic molecules based on structural information for a conformationally constrained
Radwan El-Haggar1, Ken Kamikawa, Kazuya Machi
1Department of Biological Science, Graduate School of Science, Osaka Prefecture University, Sakai, Osaka 599-8531, Japan.
Bioorganic & Medicinal Chemistry Letters
|December 25, 2009
Abstract:
Based on structural information for a peptide (P8-2KAQ) that binds to granulocyte-colony stimulating factor receptor (G-CSFR), small ligands with a biaryl scaffold were designed and their binding affinities were evaluated.
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