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In Vivo Nanovector Delivery of a Heart-specific MicroRNA-sponge
Published on: June 15, 2018
MicroRNAs in cardiovascular biology and heart disease
Daniele Catalucci1, Paolo Gallo, Gianluigi Condorelli
1Istituto di Ricovero e Cura a Carattere Scientifico Multimedica, Milan, Italy.
Abstract:
MicroRNAs play important roles in many cellular and biological functions via the regulation of mRNA target translation. In the cardiovascular field, microRNAs are now acknowledged as fundamental in regulating the expression of genes that governs physiological and pathological myocardial adaptation to stress. Here, we review recent progress in the understanding of microRNA functions and their involvement in heart disease.
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