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Sustaining improvement in door-to-balloon time over 4 years: the Mayo clinic ST-elevation myocardial infarction
David M Nestler1, Amit Noheria, Luis H Haro
1Department of Emergency Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA. nestler.david@mayo.edu
Insights
Implementing the Mayo Clinic STEMI protocol significantly reduced door-to-balloon times for ST-elevation myocardial infarction patients. This improvement in primary percutaneous coronary intervention timeliness was sustained over four years.
Area of Science:
- Cardiology
- Healthcare Systems Engineering
Background:
- Guidelines recommend door-to-balloon (DTB) times <90 minutes for ST-elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention.
- Sustained DTB performance systems of care have not been previously reported.
Purpose of the Study:
- To report on systems of care to achieve and sustain DTB performance over several years.
- To evaluate the effectiveness and durability of the Mayo Clinic STEMI protocol.
Main Methods:
- Implemented a STEMI protocol including physician activation, single call system, rapid staff response, and real-time feedback.
- Collected data on nontransferred STEMI patients pre- and post-protocol implementation.
- Analyzed DTB times for 96 patients pre-implementation and 322 patients post-implementation over a 4-year period.
Main Results:
- Median DTB decreased from 97 minutes pre-implementation to 67 minutes post-implementation (P<0.001).
- The percentage of patients with DTB <90 minutes increased from 40% to 81%.
- DTB performance remained stable over the 4-year follow-up (P=0.41).
Conclusions:
- The Mayo Clinic STEMI protocol effectively reduced DTB times for STEMI patients.
- The protocol demonstrated sustained effectiveness over a 4-year period.
- Process changes targeting primary percutaneous coronary intervention timeliness are effective and durable.
Background:
American College of Cardiology/American Heart Association guidelines recommend a door-to-balloon time (DTB) <90 minutes for nontransferred patients with ST-elevation myocardial infarction (STEMI) who undergo primary percutaneous coronary intervention. Systems of care to achieve and sustain this DTB performance over several years have not been previously reported.
Methods And Results:
The Mayo Clinic STEMI protocol was implemented in April 2004 and included activation of the cardiac catheterization laboratory by the emergency medicine physician; a single call system to activate the catheterization laboratory; catheterization laboratory staff arrival within 20 to 30 minutes of activation; and real-time performance feedback within 24 to 48 hours. Data were collected on nontransferred STEMI patients. The preimplementation group (June 2002 to March 2004) comprised 96 patients with a median DTB of 97 (interquartile range, 82, 130) minutes, and 40% had a DTB <90 minutes. The postimplementation group (May 2004 to March 2008) comprised 322 patients with a median DTB of 67 (interquartile range, 55, 82) minutes, and 81% had a DTB <90 minutes. Postimplementation DTB was significantly shorter than preimplementation DTB (P<0.001). In the 4-year follow-up after protocol implementation, the DTB performance remained stable over time (P=0.41).
Conclusions:
The Mayo Clinic STEMI protocol implemented strategies to reduce DTB for nontransferred patients with STEMI. DTB was significantly reduced, and the results were sustained over the 4-year follow-up period. Our experience demonstrates the effectiveness and durability of process changes targeting timeliness of primary percutaneous coronary intervention.
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