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Robot-Assisted Laparoscopic Splenectomy In Children: A Case Report with Literature Review
Published on: March 27, 2026
High-intensity transient signals during laparoscopic surgery in children
P Schramm1, K Engelhard, A Scherhag
1Department of Anaesthesiology, University Medical Centre of the Johannes Gutenberg-University Mainz, Langenbeckstrasse 1, 55131 Mainz, Germany. schrammp@uni-mainz.de
British Journal of Anaesthesia
|December 25, 2009
Summary
Pneumoperitoneum during laparoscopic surgery in children can increase the occurrence of high-intensity transient signals (HITS), a marker of potential cerebral emboli. This study monitored HITS before and after pneumoperitoneum to assess its impact on pediatric patients.
Area of Science:
- Pediatric Anesthesiology
- Minimally Invasive Surgery
- Cerebrovascular Physiology
Background:
- Laparoscopic surgery is increasingly common in pediatric patients.
- Pneumoperitoneum, used in laparoscopic procedures, may lead to gas emboli.
- The association between pneumoperitoneum and cerebral embolic events in children is not well-established.
Purpose of the Study:
- To investigate if pneumoperitoneum induces cerebral emboli in pediatric surgical patients.
- To assess the number and intensity of high-intensity transient signals (HITS) before and after pneumoperitoneum.
Main Methods:
- Twenty children undergoing laparoscopic surgery were monitored.
- Transcranial Doppler ultrasonography was used to detect HITS.
- Measurements of HITS, cerebral blood flow velocity, and mean arterial pressure (MAP) were taken during baseline anesthesia and during pneumoperitoneum (1.6-2.0 kPa CO2).
Main Results:
- High-intensity transient signals (HITS) were detected in 70% of patients during baseline and pneumoperitoneum.
- An additional 15% of patients developed HITS only during pneumoperitoneum.
- Mean arterial pressure (MAP) and cerebral blood flow velocity increased with pneumoperitoneum.
Conclusions:
- High-intensity transient signals (HITS) are present in a significant portion of pediatric surgical patients even before interventions.
- Pneumoperitoneum was found to further increase the occurrence of HITS in this pediatric cohort.
- Findings suggest a potential link between pneumoperitoneum and cerebral embolic signals in children.
