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Related Concept Videos

Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...

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Related Experiment Video

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Using the Open-Source MALDI TOF-MS IDBac Pipeline for Analysis of Microbial Protein and Specialized Metabolite Data
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Published on: May 15, 2019

Bisque: a platform for bioimage analysis and management.

Kristian Kvilekval1, Dmitry Fedorov, Boguslaw Obara

  • 1Center for Bio-Image Informatics, Electrical and Computer Engineering Department, University of California Santa Barbara, CA, USA. kris@cs.ucsb.edu

Bioinformatics (Oxford, England)
|December 25, 2009
PubMed
Summary
This summary is machine-generated.

Researchers need better tools for managing and analyzing microscopy images. Bisque is a new web-based platform offering organizational and quantitative analysis for 5D image data, enhancing bioimage analysis and data sharing.

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Last Updated: Jun 17, 2026

Using the Open-Source MALDI TOF-MS IDBac Pipeline for Analysis of Microbial Protein and Specialized Metabolite Data
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Published on: May 15, 2019

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
09:51

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web

Published on: July 16, 2017

Area of Science:

  • Bioimaging
  • Microscopy
  • Scientific Data Management

Background:

  • Modern microscopy generates vast amounts of complex image and metadata.
  • Proprietary formats hinder image analysis and data sharing.
  • Existing systems fail to meet researchers' needs for quantitative image analysis.

Purpose of the Study:

  • To present Bisque, a web-based platform for managing and analyzing 5D image data.
  • To provide researchers with tools for organizing and quantitatively analyzing bioimages.
  • To enable the development and sharing of novel bioimage analyses.

Main Methods:

  • Development of a web-based platform (Bisque).
  • Implementation of a flexible metadata facility.
  • Design of an open, extensible web architecture.
  • Integration of data model and analysis extensions.

Main Results:

  • Bisque provides organizational and quantitative analysis tools for 5D image data.
  • The platform is extensible, allowing adaptation to specific research needs.
  • Bisque facilitates the creation, development, and sharing of bioimage analyses.
  • Case studies demonstrate Bisque's application in various research scenarios.

Conclusions:

  • Bisque addresses the need for improved bioimage management and analysis.
  • Its flexible and open architecture empowers researchers.
  • Bisque promotes collaborative research through enhanced data sharing and analysis capabilities.