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Updated: Jun 17, 2026

Accessing the Cytotoxicity and Cell Response to Biomaterials
09:46

Accessing the Cytotoxicity and Cell Response to Biomaterials

Published on: July 8, 2021

Tissue engineering in endodontics.

Shehab El-Din M Saber1

  • 1Department of Endodontics, Faculty of Dentistry, Ain Shams University, Cairo, Egypt. Shehab007@yahoo.com

Journal of Oral Science
|December 25, 2009
PubMed
Summary
This summary is machine-generated.

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Tissue engineering uses stem cells, growth factors, and scaffolds to regenerate tissues. This review explores applying these principles to endodontics, focusing on dental pulp stem cells for immature teeth.

Area of Science:

  • Regenerative Medicine
  • Biomaterials Science
  • Endodontic Therapy

Background:

  • Tissue engineering aims to repair or replace damaged tissues using cells, signaling molecules, and structural supports.
  • Recent advancements show promise in applying tissue engineering to endodontics, particularly for dental pulp regeneration.

Purpose of the Study:

  • To review current knowledge on dental pulp stem cells (DPSCs).
  • To examine common growth factors and scaffolds used for DPSC differentiation.
  • To outline a clinical technique for immature non-vital teeth using tissue engineering.

Main Methods:

  • Literature review of studies on DPSCs, growth factors, and scaffolds in tissue engineering.
  • Analysis of existing clinical techniques for immature non-vital teeth management.

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Primary Culture of Dental Pulp Stem Cells
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Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy
11:02

Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy

Published on: April 13, 2022

Related Experiment Videos

Last Updated: Jun 17, 2026

Accessing the Cytotoxicity and Cell Response to Biomaterials
09:46

Accessing the Cytotoxicity and Cell Response to Biomaterials

Published on: July 8, 2021

Primary Culture of Dental Pulp Stem Cells
03:45

Primary Culture of Dental Pulp Stem Cells

Published on: May 5, 2023

Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy
11:02

Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy

Published on: April 13, 2022

Main Results:

  • DPSCs are a viable cell source for pulp regeneration.
  • Specific growth factors and biomimetic scaffolds can guide DPSC differentiation.
  • Tissue engineering offers a novel approach for treating immature non-vital teeth.

Conclusions:

  • Tissue engineering holds significant potential for advancing endodontic treatments.
  • Further research is needed to optimize clinical applications of DPSCs and regenerative materials.