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Post-ERCP pancreatitis in pediatric patients

Corey W Iqbal1, Todd H Baron, Christopher R Moir

  • 1Department of Surgery, Mayo Clinic, Rochester, MN 55905, USA.

Journal of Pediatric Gastroenterology and Nutrition
|December 25, 2009
PubMed

Insights

Post-ERCP pancreatitis is uncommon, affecting 2.5% of patients without chronic pancreatitis. Therapeutic procedures and chronic pancreatitis increase the risk of this complication.

Area of Science:

  • Gastroenterology
  • Pediatric Endoscopy

Background:

  • Pancreatitis is a recognized complication following endoscopic retrograde cholangiopancreatography (ERCP).
  • Assessing the incidence and severity of ERCP-associated pancreatitis is crucial for patient safety.

Purpose of the Study:

  • To determine the prevalence and severity of pancreatitis after ERCP in pediatric patients.
  • To identify risk factors associated with post-ERCP pancreatitis.

Main Methods:

  • Retrospective review of pediatric patients (<18 years) who underwent ERCP.
  • Utilized the 1991 consensus statement criteria for diagnosing post-ERCP pancreatitis.
  • Analyzed risk factors, including chronic pancreatitis and pancreatic duct stenting.

Main Results:

  • Overall prevalence of post-ERCP pancreatitis was 2.5% in patients without chronic pancreatitis (7/276 ERCPs).
  • Prevalence was higher (14.9%) in patients with chronic pancreatitis (10/67 ERCPs).
  • Diagnostic ERCPs were associated with a lower risk of pancreatitis (P<0.01), while pancreatic duct stenting was a risk factor in chronic pancreatitis patients (P=0.02).

Conclusions:

  • Post-ERCP pancreatitis prevalence is low (2.5%) when excluding patients with chronic pancreatitis.
  • Therapeutic ERCP procedures and the presence of chronic pancreatitis are identified as risk factors for developing pancreatitis.
Abstract

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