Related Experiment Video
Updated: Jun 17, 2026
Preparation of Zinc Oxide Nanoparticles and the Evaluation of their Antibacterial Effects
Published on: September 27, 2024
New conjugated benzothiazole-N-oxides: synthesis and biological activity
Peter Gajdos1, Peter Magdolen, Pavol Zahradník
1Department of Organic Chemistry, Faculty of Natural Sciences, Comenius University, Mlynskádolina CH-2, 842 15 Bratislava, Slovakia.
Abstract:
Eleven new 2-styrylbenzothiazole-N-oxides have been prepared by aldol - type condensation reactions between 2-methylbenzothiazole-N-oxide and para-substituted benzaldehydes. Compounds with cyclic amino substituents showed typical push-pull molecule properties. Four compounds were tested against various bacterial strains as well as the protozoan Euglena gracilis as model microorganisms. Unlike previously prepared analogous benzothiazolium salts, only weak activity was recorded.
